EVALUATION OF SCREENING TESTS FOR CONGENITAL CYTOMEGALOVIRUS INFECTION
- 1 February 2008
- journal article
- research article
- Published by Wolters Kluwer Health in The Pediatric Infectious Disease Journal
- Vol. 27 (2) , 182-184
- https://doi.org/10.1097/inf.0b013e318161a2d5
Abstract
Although the use of dried blood spots has been proposed for screening of newborns with congenital cytomegalovirus infection, viral loads in blood were significantly smaller than those in urine (P < 0.001), and DNA recovery from dried blood spots using the thermal shock procedure was inefficient. In contrast, our urine-based screening program identified asymptomatic cases with low viral loads in blood.Keywords
This publication has 10 references indexed in Scilit:
- Real-Time PCR Assay Using Specimens on Filter Disks as a Template for Detection of Cytomegalovirus in UrineJournal of Clinical Microbiology, 2007
- Etiology of Severe Sensorineural Hearing Loss in Children: Independent Impact of Congenital Cytomegalovirus Infection andGJB2MutationsThe Journal of Infectious Diseases, 2007
- Diagnosis of Human Congenital Cytomegalovirus Infection by Amplification of Viral DNA from Dried Blood Spots on Perinatal CardsThe Journal of Molecular Diagnostics, 2006
- Multicity Italian Study of Congenital Cytomegalovirus InfectionThe Pediatric Infectious Disease Journal, 2006
- Neonatal Cytomegalovirus Blood Load and Risk of Sequelae in Symptomatic and Asymptomatic Congenitally Infected NewbornsPediatrics, 2006
- Diagnosis of congenital cytomegalovirus infection by detection of viral DNA in urine poolsJournal of Virological Methods, 2005
- Congenital Cytomegalovirus Infection: Association between Virus Burden in Infancy and Hearing LossThe Journal of Pediatrics, 2005
- Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, JapanBMC Infectious Diseases, 2004
- Usefulness of blood and urine samples collected on filter paper in detecting cytomegalovirus by the polymerase chain reaction techniqueJournal of Virological Methods, 2001
- Newborn hearing screening: Will children with hearing loss caused by congenital cytomegalovirus infection be missed?The Journal of Pediatrics, 1999