Studies on the Particles of Infantile Gastroenteritis Virus (Orbivirus Group)

1 January 1976

journal article
research article
Published by S. Karger AG in Intervirology

Vol. 7 (4-5) , 181-191
https://doi.org/10.1159/000149951

Abstract

Isopycnic centrifugation of infantile gastroenteritis virus (orbivirus group) in a CsCl gradient produced up to 4 bands at densities 1.38, 1.36, 1.30 and 1.28 g/ml. The particles in the bands had sedimentation coefficients of 380-400S, 520-530S, 270-280S and 320-330S, respectively. Whereas the 1.38 and 1.36 g/ml particles contained RNA, the 1.30 and 1.28 g/ml particles lacked RNA. Upon heating at 37.degree. C, the 1.36 g/ml particles broke down into particles of higher and lower density.

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