High-Performance Liquid Chromatography/Mass Spectrometry Analysis of Botanical Medicines and Dietary Supplements: A Review
Open Access
- 1 September 2003
- journal article
- review article
- Published by Oxford University Press (OUP) in Journal of AOAC INTERNATIONAL
- Vol. 86 (5) , 873-881
- https://doi.org/10.1093/jaoac/86.5.873
Abstract
This article reviews research on the qualitative and quantitative analysis by high-performance column liquid chromatography/mass spectrometry (LC/MS) and LC/tandem mass spectrometry (LC/MS/MS) of botanical drugs, drug substances or preparations, and finished botanical products. In addition, LC/MS and LC/MS/MS techniques and commercial instruments are described and compared briefly, and prospects for future use of these methods for the analysis of botanicals are suggested. Some applications of direct MS without LC are also described.Keywords
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