New potent angiotensin II receptor antagonists containing phenylthiophenes and phenylfurans in place of the biphenyl moiety.
- 30 June 1993
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 3 (6) , 1119-1124
- https://doi.org/10.1016/s0960-894x(00)80299-1
Abstract
No abstract availableThis publication has 10 references indexed in Scilit:
- Nonpeptide angiotensin II receptor antagonists: synthetic and computational chemistry of N-[[4-[2-(2H-tetrazol-5-yl)-1-cycloalken-1-yl]phenyl]methyl]imidazole derivatives and their in vitro activityJournal of Medicinal Chemistry, 1992
- New nonpeptide angiotensin II receptor antagonists. 1. Synthesis, biological properties and structure-activity relationships of 2-alkylbenzimidazole derivativesJournal of Medicinal Chemistry, 1992
- Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonistsJournal of Medicinal Chemistry, 1991
- Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensivesJournal of Medicinal Chemistry, 1991
- DuP 532: A second generation of nonpeptide angiotensin II receptor antagonistsBiochemical and Biophysical Research Communications, 1991
- Renin inhibitorsMedicinal Research Reviews, 1990
- The renin-angiotensin systemTrends in Pharmacological Sciences, 1987
- Synthesis and spectroscopic characteristics of aryltrimethyl-silicon, -germanium, and -tin compoundsJournal of Organometallic Chemistry, 1987
- The Palladium‐Catalyzed Cross‐Coupling Reactions of Organotin Reagents with Organic Electrophiles [New Synthetic Methods (58)]Angewandte Chemie International Edition in English, 1986
- Renin-angiotensin system: biochemistry and mechanisms of action.Physiological Reviews, 1977