Effect of Progressive Changes in Body Temperature of Rats on Tissue Oxygen-tensions, in Relation to Radiosensitivity
- 1 January 1963
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 6 (6) , 529-540
- https://doi.org/10.1080/09553006314550641
Abstract
Oxygen-tens ions, measured polarographically in tissues of rats subjected to progressive hypothermia and hyperthermia, are reported. Corresponding radiosensitivity values have been estimated and indicate that both hypothermia (15[degree]C) and hyperthermia (41[degree]C) cause radioprotection due to "oxygen effect", with a reduction in radiosensitivity of haemopoietic tissues to ~ 75 per cent and 85 per cent of maximum values respectively. The physiological reasons for these findings are discussed.Keywords
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