APPARENT MUTAGENIC EFFECT OF THYMINE DEFICIENCY FOR A THYMINE-REQUIRING STRAIN OF ESCHERICHIA COLI

Abstract
Cultivation (at 37[degree]C) of a thymine-requiring strain (15T-) of E. coli in the absence of thymine, but with glucose as the sole C source, leads to an increased frequency of streptomycin-resistant mutants. Under the experimental conditions (incubation of cells impinged on millipore filters) no selection for or against streptomycin-resistant mutants was detected.

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