A Factor in Normal Human Blood which Participates in Streptococcal Fibrinolysis
Open Access
- 1 October 1941
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 42 (2) , 109-116
- https://doi.org/10.4049/jimmunol.42.2.109
Abstract
Summary: Fibrinolysin of a group A strain (Co) of hemolytic streptococcus does not exert its characteristic rapid action on human fibrin, if the fibrin is sufficiently pure. Such human fibrin can be rendered susceptible to the fibrinolysin by the addition of a lytic factor present in the euglobulin fraction of normal human serum. The human lytic factor also renders preformed rabbit fibrin susceptible to the group A fibrinolysin. The lytic factor contaminates the usual crude fibrin clot but is distinct from thrombin and fibrinogen.Keywords
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