Evidence for a Major Locus as Well as a Multifactorial Component in the Regulation of Human Red Blood Cell Catechol-O-Methyl-Transferase Activity
- 1 January 1982
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 32 (2) , 76-79
- https://doi.org/10.1159/000153264
Abstract
Complex segregation analysis has shown the red blood cell catechol-O-methyltransferase (COMT) activity in man to be regulated by a major locus (d = 0.27) plus a multifactorial component (H = 0.25). The frequency of the gene which gives low COMT values was 0.46.Keywords
This publication has 1 reference indexed in Scilit:
- Skewness in Commingled DistributionsBiometrics, 1976