Inhibition of Experimental Cholesterol Arteriosclerosis by Ultraviolet Irradiation

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Abstract
IT is generally agreed that ultraviolet irradiation of cholesterol alters the physicochemical nature of this substance, although it is not clear what kind of process is responsible. Stavely and Bergmann,1 and Mayneord and Roe2 believe that some ozonide is formed, because cholesterol irradiated without access of oxygen or without moisture does not blacken photographic emulsions, whereas it does so if irradiated with access of oxygen or if moisture is present. Roffo3 has maintained that, because of its oxidation after ultraviolet irradiation, cholesterol becomes carcinogenic. His assertion has not been confirmed by others.4 Conversely, his contention that carcinogenic substances are formed . . .