Insulin Rescues Retinal Neurons from Apoptosis by a Phosphatidylinositol 3-Kinase/Akt-mediated Mechanism That Reduces the Activation of Caspase-3
Open Access
- 1 August 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (35) , 32814-32821
- https://doi.org/10.1074/jbc.m104738200
Abstract
No abstract availableKeywords
This publication has 67 references indexed in Scilit:
- Sustained phosphorylation and activation of protein kinase B correlates with brain-derived neurotrophic factor and insulin stimulated survival of cerebellar granule cellsNeuroscience Letters, 1999
- Insulin-like Growth Factor-1-mediated Neuroprotection against Oxidative Stress Is Associated with Activation of Nuclear Factor κBJournal of Biological Chemistry, 1999
- Involvement of p53 in DNA Strand Break‐induced Apoptosis in Postmitotic CNS NeuronsEuropean Journal of Neuroscience, 1996
- Signaling via the insulin-like growth factor-I receptor: Does it differ from insulin receptor signaling?Cytokine & Growth Factor Reviews, 1996
- Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in cultureNeuron, 1995
- Insulin Activates Nuclear Factor κB in Mammalian Cells through a Raf-1-mediated PathwayJournal of Biological Chemistry, 1995
- Peroxynitrite‐Induced Cytotoxicity in PC12 Cells: Evidence for an Apoptotic Mechanism Differentially Modulated by Neurotrophic FactorsJournal of Neurochemistry, 1995
- Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neuronesBrain Research, 1993
- Release of Immunoreactive Insulin from Rat Brain Synaptosomes Under Depolarizing ConditionsJournal of Neurochemistry, 1990
- Retinal insulin receptors: localization using a polyclonal anti-insulin receptor antibodyBrain Research, 1988