Immunohistochemical localization of plasma retinolbinding protein and prealbumin in human pancreatic islets
- 1 April 1986
- journal article
- research article
- Published by Springer Nature in Journal of Molecular Histology
- Vol. 18 (4) , 164-168
- https://doi.org/10.1007/bf01676116
Abstract
This study was undertaken, employing the immunoenzyme method, to confirm the presence of retinol-binding protein in human pancreatic islets, and to compare its distribution with that of prealbumin, insulin, glucagon, somatostatin and pancreatic polypeptide. It was found that most islet cells contained retinol-binding protein, although centrally located cells showed stronger reactivity than those in the peripheral region. The distribution of each of the five polypeptides differed from that of retinolbinding protein, indicating that these peptides did not cross-react with anti-retinol-binding protein antibody. Islet cells which contained prealbumin, on the other hand, were mostly classified as A cells. Further studies are necessary to confirm whether the islet cells produce retinol-binding protein or only store it.This publication has 21 references indexed in Scilit:
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