Arousal, Suppression, and Persistence: Frustration Theory, Attention, and its Disorders

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Abstract
In this article I deal first with the relevance of theories of frustration and general persistence to the concept of attention, and offer an interpretation of attention deficit hyperactivity disorder (ADHD) in terms of persistence deficits. After summarising these theories and the manner in which they integrate the concepts of arousal, suppression, and persistence, I describe relevant developmental work in infant rats comprising an ontogenetic sequence of first appearance of a number of reward-schedule effects, and suggest their possible utility as a behavioural assay. Finally, I briefly review neuroanatomical and behavioural work on fetal alcohol and its possible implications for theories of attention and hyperactivity, and provide some data from experiments on fetal alcohol effects in infant rats which may have some relevance to such an interpretation.