Kartagener's Syndrome with Motile Spermatozoa
- 28 October 1982
- journal article
- case report
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 307 (18) , 1131-1133
- https://doi.org/10.1056/nejm198210283071807
Abstract
Immotile cilia syndrome is an inherited disorder characterized by recurrent sinopulmonary infections, reduced fertility in women, and sterility due to immobile spermatozoa in men.1 , 2 When situs inversus is encountered — in about half the cases — the disorder is referred to as Kartagener's syndrome.The clinical effects of this syndrome are caused by the inability of ciliated structures to beat effectively.3 , 4 In the respiratory tract this inability presumably causes impaired clearance of mucus and inhaled particulates and results in the chronic infections of the sinuses and bronchial tree that are so characteristic of the disease. The genetic defect in ciliary . . .Keywords
This publication has 8 references indexed in Scilit:
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- Transposition of Ciliary MicrotubulesNew England Journal of Medicine, 1980
- Ciliary motility in the ‘immotile cilia syndrome’Respiratory Medicine, 1980
- Flagellar mutants in man: On the heterogeneity of the immotile-cilia syndromeJournal of Ultrastructure Research, 1979
- Cilia with Defective Radial SpokesNew England Journal of Medicine, 1979
- Kartagener's syndrome and the syndrome of immotile ciliaHuman Genetics, 1979
- The Immotile-Cilia SyndromeNew England Journal of Medicine, 1977
- Absence of Arms in the Axoneme of Immobile Human SpermatozoaBiology of Reproduction, 1975