Increased Metabolic Rate in Rats after X-Irradiation

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Abstract
Irradiated rats fell into 4 groups: (1) those which died 3-5 days after irradiation, (2) those which died 9-10 days after exposure, (3) survivors of doses in the lethal range, and (4) survivors of sublethal doses. The 1st group showed an elevation of O2 con-sumption of 35% within 24 hrs., while in the 2d group the O2 consumption increased an avg. of 58% and then declined just prior to death. Rats which survived doses of 648 r showed an avg. increase in O2 consumption of 32% during the first week while at doses from 54 to 432 r there was an increase of about 8%. Increased metabolism did not coincide with wt. loss either in time course or dose dependence.