A Comparison of Growth Inhibition of Tetrahymena furgasoni by C19 and C21 Steroids
- 30 April 1982
- journal article
- research article
- Published by Wiley in The Journal of Protozoology
- Vol. 29 (2) , 239-242
- https://doi.org/10.1111/j.1550-7408.1982.tb04019.x
Abstract
The growth inhibition of T. furgasoni (once known as T. pyriformis W) by C19 and C21 steroids of similar structure was measured by determining cell population at 24 and 48 h following addition of the steroid. A cis-fusion of the A/B rings junction, unsaturation at C-1.2, or C-4.5 and carbonyl substitution all enhanced inhibition; the presence of 2 hydroxyl groups decreased inhibition. The transformation of C19 and C21 steroids by this protozoon may be part of a detoxication mechanism.This publication has 17 references indexed in Scilit:
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