Effects of perhexiline maleate on coronary flow distribution in the ischemic canine myocardium.
- 1 July 1976
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 54 (1) , 14-20
- https://doi.org/10.1161/01.cir.54.1.14
Abstract
Intravenous perhexiline maleate in a canine preparation with fixed coronary flow increases coronary diastolic pressure. It also redistributes coronary flow so as to preserve endocardial flow. Myocardial oxygen consumption was reduced and lactate uptake enhanced by the drug. It had no effect upon the threshold for ischemic-induced left ventricular failure.This publication has 5 references indexed in Scilit:
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