Studies on the mode of action of excess of vitamin A. 3. Release of a bound protease by the action of vitamin A
- 1 June 1961
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 79 (3) , 509-512
- https://doi.org/10.1042/bj0790509
Abstract
Participate preparations from rat liver sus-pended in 0.25 M-sucrose and treated with vitamin A release a proteolytic enzyme with an acid pH optimum. The action of the vitamin on the particles is dependent upon temperature and pH. The enzyme, after release by hypo-osmotic treatment, is not affected by the vitamin. The relationship of this effect to the action of vitamin A on intact tissue is discussed.Keywords
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