Angiotensin-Converting Enzyme Inhibition in Infarct-Induced Heart Failure in Rats: Bradykinin Versus Angiotensin II
- 1 October 1994
- journal article
- research article
- Published by Oxford University Press (OUP) in European Journal of Preventive Cardiology
- Vol. 1 (3) , 255-262
- https://doi.org/10.1177/174182679400100311
Abstract
Background: The beneficial effects of angiotensin-converting enzyme (ACE) inhibitors in the prevention of heart failure following myocardial infarction are widely accepted. However, the underlying mechanisms are still a matter of discussion. We therefore investigated the relative contribution of the inhibition of the breakdown of bradykinin and of the inhibition of angiotensin-II synthesis to the beneficial actions of ACE inhibitors in chronic heart failure following myocardial infarction.Keywords
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