Hours of work and the risk of developing impaired fasting glucose or type 2 diabetes mellitus in Japanese male office workers

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Abstract
OBJECTIVE To investigate the association between duration of overtime and the development of impaired fasting glucose (IFG) or type 2 diabetes mellitus (DM). METHODS A cohort of 1266 Japanese male office workers aged 35–59 years and free of IFG (fasting plasma glucose concentration 6.1–6.9 mmol/l), type 2 DM (fasting plasma glucose concentration of 7.0 mmol/l or more or taking hypoglycaemic medication), history of diabetes, or medication for hypertension were re-examined over 5 successive years after their initial examinations in 1994. RESULTS 138 men developed IFG or type 2 DM during the 5736 person-years of follow up. After controlling for potential predictors of diabetes, the relative risks of IFG or type 2 DM, compared with those who worked CONCLUSION Longer overtime is a negative risk factor for the development of IFG or type 2 DM in Japanese male office workers.