Fentanyl Related Overdose*

Abstract
An accidental overdose fatality resulting from the intravenous injection of Sublimaze® (fentanyl) is presented. Fentanyl was extracted from postmortem specimens by a basic extraction procedure. Benzene was used as the extraction solvent and alfentanyl as the internal standard. The drug was quantitated by electron impact gas chromatography/mass spectrometry in the selected ion monitoring (SIM) mode. Fentanyl concentrations were, blood, 4.0/µg/L; urine, 13.0/µg/L; liver, 9.7/µg/kg, and kidney, 8.6/µg/kg.

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