Activity of tetroxoprim and sulphadiazine alone and in combination on Gram-negative bacteria
- 1 November 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 5 (upplement ) , 45-47
- https://doi.org/10.1093/jac/5.supplement_b.45
Abstract
The activity oftetroxoprim and sulphadiazine, alone and in a combination of 1:4 was studied against 183 common gram-negative bacteria. Maximum synergy was found at a level of 4 mg/l of the combination and most strains of the sensitive population were susceptible to 4 mg/l oftetroxoprim. The MBC of the majority of strains was the same as the MIC. Trimethoprim was two to three times more active than tetroxoprim.Keywords
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