Elastic Rod Model of a DNA Loop in theOperon
- 6 December 1999
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 83 (23) , 4900-4903
- https://doi.org/10.1103/physrevlett.83.4900
Abstract
We use the theory of elasticity to compute the shape of the DNA loop bridging the gap in the crystal structure of the lac repressor-DNA complex. The Kirchhoff system of equations with boundary conditions derived from the crystal structure is solved using a continuation method. This approach can be applied effectively to find coarse-grained conformational minima of DNA loops.Keywords
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