Studies on the mechanism of denaturation of cytochrome P-450 by cyclophosphamide and its metabolites.
Open Access
- 1 November 1981
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 256 (22) , 11691-11701
- https://doi.org/10.1016/s0021-9258(19)68462-0
Abstract
No abstract availableThis publication has 35 references indexed in Scilit:
- Inactivation of hepatic cytochrome P-450 by allenic substratesBiochemical and Biophysical Research Communications, 1980
- Protection by N-acetylcysteine of cyclophosphamide metabolism - related invivo depression of mixed function oxygenase activity and invitro denaturation of cytochrome P-450Biochemical and Biophysical Research Communications, 1980
- Denaturation of cytochrome P-450 by cyclophosphamide metabolitesBiochemical and Biophysical Research Communications, 1978
- Studies on the binding of [3H-chloroethyl]-cyclophosphamide and 14[C-4]-cyclophosphamide to hepatic microsomes and native calf thymus DNALife Sciences, 1978
- Evidence for the formation of a protein bound hydrodisulfide resulting from the microsomal mixed function oxidase catalyzed desulfuration of carbon disulfideBiochemical and Biophysical Research Communications, 1975
- Isolation and mass spectral identification of blood metabolities of cyclophosphamide: Evidence for phosphoramide mustard as the biologically active metaboliteJournal of Mass Spectrometry, 1975
- Oxidative metabolism of carbon disulphide by the rat: Effect of treatments which modify the liver toxicity of carbon disulphideChemico-Biological Interactions, 1973
- Drug metabolism after repeated treatments with cytotoxic agentsPublished by Elsevier ,1971
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970
- The effect of cytotoxic agents on drug metabolismPublished by Elsevier ,1970