CLASSICAL PATHWAY COMPLEMENT ACTIVATION IN ASSOCIATION WITH PARAPROTEINEMIA
- 1 January 1977
- journal article
- research article
- Vol. 33 (4) , 517-521
Abstract
Five of 23 patients with paraproteinemia (2 Ig[immunoglobulin]M, 3 IgG) exhibited marked classical pathway complement [C] activation. The mechanisms of hypocomplementemia proposed for the 5 patients are cryoglobulinemia in 1 and in vivo Ig aggregation in the other 4. Three further patients had a low Clq and 3 a low C3 unassociated with any other C abnormality. No association with any particular IgG subclass or obvious clinical abnormality existed in association with hypocomplementemia.This publication has 8 references indexed in Scilit:
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