Pulmonary “Hypersensitivity” Reactions Induced by Transfusion of Non-HL-A Leukoagglutinins

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Abstract
In two cases of normovolemic pulmonary edema associated with whole-blood transfusion, clinical manifestations included abrupt onset of chills, fever, tachycardia, dyspnea and cough. Cyanosis and hypotension occurred in the more severe case, and bilateral pulmonary infiltrates without confirmatory evidence of circulatory overload were present in both.