Effect of surface boundary on time-resolved reflectance: measurements with a prototype endoscopic catheter

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Abstract
The implementation of time-resolved reflectance, R(t), measurements via endoscopes during medical procedures may provide an important diagnostic tool for medicine. This paper presents initial studies on a prototype catheter device suitable for the biopsy channel of an endoscope. A pair of optical fibers, one a source and one a collector, were adjoined with epoxy to create a single catheter tip. Such close proximity of two fibers is a special case of the generic R(r,t) measurement, where the fiber separation (r) approaches zero. The influence of an air/tissue surface boundary on the time-resolved collection of photons backscattered by a turbid media is presented. The catheter was either (1) place on the surface of an aqueous turbid solution, or (2) imbedded deep within the volume and distant from the surface or any boundaries. The time course of photon collection was found to be strongly influenced by the surface boundary. Such boundary effects are pertinent to the design of time-resolved catheters which require close spacing of the source and collector fibers.© (1991) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.

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