24-Hour Rhythms at Several Levels of Integration in Mice on Different Lighting Regimens.

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Abstract
The following variables were studied in the mouse under conditions standardized for evaluation of 24-hour periodicity: glucose and "corticosterone" in blood; mitoses in pinnal epidermis and hepatic parenchyma; liver glycogen and the hepatic metabolism of cytoplasmic phospholipid and ribonucleic acid and of nuclear deoxyribonucleic acid. For each variable, data obtained with light from 6 p.m. to 6 a.m. alternating with 12 hours of darkness, were compared with data obtained with light from 6 a.m. to 6 p.m. A shift in timing of 24-hour rhythms, following the inversion of lighting regimen came clearly and consistently to the fore.

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