The Pharmacological and Pathological Studies on Several Hepatic Protective Crude Drugs from Taiwan (II)

Abstract
Four crude drug extracts of Solanum incanum (entire plant), Ixeris chinensis (entire plant), Gardenia jasminoides (wild and cultivated, fructus) were adminstered to rats as dose of 1.0 g/kg, I.P. injection to screen the liver protective effect on CC14 induced hepatotoxicity. The acute increase of transaminase SGOT and SGPT levels that was caused by CC14 (1.0 ml/kg) S.C. injection can be significantly improved when treated with Solanum incanum(pIxeris chinensis(pGardenia jasminoides (cultivated) (pGardenia jasminoides(pS. incanum and .I. chinesis administration, while the effect of treatment with G. jasminoides (cultivated) demonstrated a moderate protective action and little histopathological change by G. jasminoides (wild). In contrast to B. chinese, which has been reported previously as a treatment criteria, the S. incanum(pI. chinensis(p4 induced hepatic injury.

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