Electrophoretic Migration Pattern of Serum Glutamic Oxalacetic Transaminase
- 1 February 1958
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 4 (1) , 13-21
- https://doi.org/10.1093/clinchem/4.1.13
Abstract
Using the combined technics of the ionographic separation of serum proteins in a paper-stabilized medium, as described by McDonald et al. (16, 17, 18), and the spectrophotometric procedure for the determination of transaminase activity developed by Karmen (3, 14), the electrophoretic migration pattern of the enzyme glutamic oxalacetic transaminase in rat serum has been examined. The major portion of the transaminase activity has been found to be associated with the α-2 globulin fraction of the serum proteins. Further evidence has been presented for the assumption of a nonionic linkage between the enzyme and its coenzyme, pyridoxal phosphate.Keywords
This publication has 2 references indexed in Scilit:
- Diagnostic and Prognostic Significance of Serum Transaminase Levels in Coronary Occlusive DiseaseCirculation, 1957
- Lipid NomenclatureCirculation Research, 1956