Monoamine oxidases: to inhibit or not to inhibit.
- 1 March 2003
- journal article
- research article
- Published by Bentham Science Publishers Ltd. in Mini-Reviews in Medicinal Chemistry
- Vol. 3 (2) , 129-136
- https://doi.org/10.2174/1389557033405287
Abstract
Abstract: Monoamine oxidase (MAO) inhibitors were developed as antidepressants but many drugs, including the novel oxazolidinone antibacterial agents, share similar molecular properties and have MAO inhibitory activity. Factors important for binding antidepressants and modifications to decrease binding of oxazolidinones to avoid undesirable vascular effects are discussed.Keywords
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