The 3′‐terminal untranslated region of alfalfa mosaic virus RNA 4 facilitates the RNA entry into translation in a cell‐free system
- 1 July 1993
- journal article
- Published by Wiley in FEBS Letters
- Vol. 326 (1-3) , 264-266
- https://doi.org/10.1016/0014-5793(93)81804-9
Abstract
In order to understand the role of the 3′‐terminal untranslated region (3′‐UTR) of alfalfa mosaic virus (A1MV) RNA 4 in viral RNA translation we have constructed the RNA derivatives differing in the length of their 3′‐terminal portions and expressed them in a wheat germ extract. The result shows that the removal of the 3′‐UTR from A1MV RNA 4 causes a lagged RNA translation in the cell‐free system as compared with the translation of the full length RNA 4, thus suggesting the involvement of the 3′‐UTR in the translation initiation pathway.Keywords
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