Fetus in fetu:Molecular analysis of a fetiform mass

Publisher Website
Google Scholar
Abstract
Fetus‐in‐fetu is a rare condition presenting as a calcified intra‐abdominal mass in the new‐born infant. Over 50 cases of fetus‐in‐fetu have been reported since 1800. Karyotype analysis in 8 cases and protein polymorphisms in 4 documented identical finding in the host and fetiform mass. We report a case of fetus‐in‐fetu in a newborn female including cytogenetic and molecular studies of both the host and mass. Genotypic information from 7 polymerase chain reaction (PCR) assays representing 4 chromosomes demonstrates heterozygous and identical alleles in the infant and fetus‐in‐fetu at all loci studied. A review of the literature is provided including a discussion regarding the impact of moleculer data on present hypotheses of fetus‐in‐fetu pathogenesis.

This publication has 34 references indexed in Scilit: