Production of ammonia by surviving kidney tissue
- 1 January 1930
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 24 (5) , 1564-1571
- https://doi.org/10.1042/bj0241564
Abstract
The ammonia-producing system acting only under aerobic conditions and having an optimum activity at pH 5.2 or lower is probably the system concerned in the physiological production of ammonia by the kidney, since this is greatest when the urine is acid. Severely nephritic (uranium) kidney tissue causes a marked decrease in ammonia production by this system; excretion of ammonia in uranium nephritis is also very low. The possibility of adenylic acid and urea being precursors is discussed. Urea, as well as ammonia, is formed aerobically by normal kidney tissue at pH 7.3.This publication has 3 references indexed in Scilit:
- Studies in the metabolism of tissues growing in vitroBiochemical Journal, 1929
- The production of ammonia by surviving kidney tissueBiochemical Journal, 1929
- Gastric UreaseBiochemical Journal, 1924