PULMONARY CAPILLARY BLOOD FLOW IN MAN 12
Open Access
- 1 September 1955
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 34 (9) , 1380-1390
- https://doi.org/10.1172/jci103187
Abstract
A method is described for instantaneous measurement of pulmonary capillary blood flow in man. The subject sits in an airtight body plethysmograph; continuous records of plethysmograph pressure and the subject''s ecg are made during breathholding after N2O inhalation. As the N2O is absorbed by the blood flowing through the subject''s alveolar capillaries, the gas pressure within the body plethysmograph falls. The fall in pressure is proportional to the capillary blood flow and is pulsatile. The maximal rate of blood flow is in time with the T wave, while the slowest rate of flow closely follows the QRS complex.Keywords
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