• 1 January 1981
    • journal article
    • research article
    • Vol. 42  (12) , 2065-2067
Abstract
Quantitative interactions of S. aureus protein A (SPA) and canine Ig are described. The S. aureus Cowan strain I bound canine IgG, IgM and IgA; binding was not observed with the SPA-negative Wood 46 strain of S. aureus. In a quantitative adsorption experiment, the IgA, though present in the lowest amounts in the samples, appeared to be substantially bound by SPA. Adsorption of sera with SPA-negative Wood strain bacteria resulted in nonspecific protein losses in supernatants of 0-15%.