EFFECT OF CIGARET SMOKE ON THE pH OF THE THROAT

1 March 1943

journal article
research article
Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery

Vol. 37 (3) , 404-410
https://doi.org/10.1001/archotol.1943.00670030414007

Abstract

Despite the fact that the annual consumption of cigarets by the American public has been continually increasing, little substantial scientific research on the effect of cigaret smoke on the upper respiratory tract of normal persons has been recorded in the medical literature. Recently, the role of the hygroscopic agent—glycerin or diethylene glycol—in irritation of the respiratory tract has received some interest. Various approaches to the problem have been used in the published reports. Mulinos and Osborne¹and Haag²studied the edema-producing properties of smoke solutions in the conjunctival sacs of rabbits. Flinn³and Ballenger and Johnson⁴made clinical observations on irritation of the pharyngeal mucous membranes. Holck and Carlson⁵used the salivary response as their index of irritation. All these investigators used glycerin-treated cigarets and diethylene glycol-treated cigarets. EXPERIMENTAL INVESTIGATION In this study I have utilized a silver-silver chloride glass electrode in conjunction with the Coleman electrometer for the purpose

Keywords

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EFFECT OF SILVER PREPARATIONS AND ANTISEPTICS ON THE pH OF NASAL SECRETIONS IN SITU
JAMA Otolaryngology–Head & Neck Surgery, 1941