Erythema Multiforme: A Review of Its Characteristics, Diagnostic Criteria, and Management

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Abstract
Erythema multiforme is a distinctive hypersensitivity syndrome characterized by skin and mucous membrane lesions and, in its more severe forms, mucosal lesions with constitutional symptoms and, at times, visceral involvement.1,2 It is usually considered acute and self-limiting, but recent observations indicate that it may also behave as a chronic recurrent disorder in many people.1,3,4 The disorder may occur at any age, with its highest incidence in young adults 20 to 40 years of age; as many as 20% of cases are seen in children and adolescents.2

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