Facial expression recognition and subthalamic nucleus stimulation

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Abstract
Background: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) improves motor signs in Parkinson’s disease. However, clinical studies suggest that DBS of the STN may also affect cognitive and emotional functions. Objective: To study the impact of STN stimulation in Parkinson’s disease on perception of facial expressions. Results: There was a selective reduction in recognition of angry faces, but not other expressions, during STN stimulation. Conclusions: The findings may have important implications for social adjustment in these patients.