Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma
Open Access
- 3 January 1991
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 324 (1) , 1-8
- https://doi.org/10.1056/nejm199101033240101
Abstract
Experimental evidence suggests that the growth of a tumor beyond a certain size requires angiogenesis, which may also permit metastasis. To investigate how tumor angiogenesis correlates with metastases in breast carcinoma, we counted microvessels (capillaries and venules) and graded the density of microvessels within the initial invasive carcinomas of 49 patients (30 with metastases and 19 without).Keywords
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