Adrenocortical Response to Novelty and Noxious Stimulation
- 1 January 1967
- journal article
- research article
- Published by S. Karger AG in Neuroendocrinology
- Vol. 2 (4) , 209-212
- https://doi.org/10.1159/000121549
Abstract
Rats were either subjected to high levels of electric shock or merely placed in the experimental cage for a comparable period of time. The experiment was conducted at the "peaks" and "troughs" of the adrenocortical circadian rhythm. The plasma corticosterone levels did not differ significantly in these 2 groups of rats, though both had significantly higher corticosterone levels than control animals. The data demonstrate that exposure to a new environment, or novelty, may contribute significantly to the adrenocortical response often attributed entirely to the effects of noxious or painful stimulation.Keywords
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