Does calmodulin play a functional role in phototransduction?

Abstract
Molday and Hsu review results from invitroexperiments, which indicate that Ca-bound calmodulin reduces the cGMP sensitivity of the cyclic nucleotide-gated channel of photoreceptor cells, and speculate about the role they might play in the recovery of the light response. We discuss results from invivoexperiments that argue against the participation of Ca-calmodulin in photorecovery.
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