Effects of pure carbon monoxide gas injection into the peritoneal cavity of dogs
- 1 May 1959
- journal article
- research article
- Published by American Physiological Society in Journal of Applied Physiology
- Vol. 14 (3) , 311-312
- https://doi.org/10.1152/jappl.1959.14.3.311
Abstract
Relatively large quantities of pure carbon monoxide (500 ml) were injected into the peritoneal cavity of normal dogs, CO-acclimatized dogs and altitude-acclimatized dogs. Withdrawal and analysis of the gas at timed intervals revealed a rise in oxygen tension from zero to values which were 2frac12 times the PaOO2. The PiOO2 (intraperitoneal O2 tension) in the acclimatized dogs attained values significantly higher than for the normal dogs. The PiCOCO2 (intraperitoneal CO2 tension) in all dogs approximated the value in normal animals. At no time after the injection did the COHb exceed a 40–50% concentration level. The physiologic mechanism of the observed phenomena is discussed. Submitted on September 22, 1958Keywords
This publication has 1 reference indexed in Scilit:
- Protective Action of Carbon Monoxide in Mammalian Whole-Body X-IrradiationRadiation Research, 1955