Specificity of inhibitors of serine palmitoyltransferase (SPT), a key enzyme in sphingolipid biosynthesis, in intact cells
- 23 March 2000
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 59 (10) , 1211-1216
- https://doi.org/10.1016/s0006-2952(00)00251-3
Abstract
No abstract availableKeywords
Funding Information
- Japan Science and Technology Agency
- Ministry of Education
This publication has 21 references indexed in Scilit:
- Genetic Evidence for ATP-dependent Endoplasmic Reticulum-to-Golgi Apparatus Trafficking of Ceramide for Sphingomyelin Synthesis in Chinese Hamster Ovary CellsThe Journal of cell biology, 1999
- Mammalian Cell Mutants Resistant to a Sphingomyelin-directed CytolysinJournal of Biological Chemistry, 1998
- Catalytic Asymmetric Syntheses of Antifungal Sphingofungins and Their Biological Activity as Potent Inhibitors of Serine Palmitoyltransferase (SPT)Journal of the American Chemical Society, 1998
- Dual Roles of Sphingolipids in Signaling of the Escape from and Onset of Apoptosis in a Mouse Cytotoxic T-cell Line, CTLL-2Journal of Biological Chemistry, 1996
- Potent Immunosuppressants, 2-Alkyl-2-aminopropane-1,3-diolsJournal of Medicinal Chemistry, 1996
- N,N-Dimethylsphingosine Inhibition of Sphingosine Kinase and Sphingosine 1-Phosphate Activity in Human PlateletsBiochemistry, 1996
- Serine Palmitoyltransferase Is the Primary Target of a Sphingosine-like Immunosuppressant, ISP-1/MyriocinBiochemical and Biophysical Research Communications, 1995
- Inhibition of serine palmitoyl-transferase activity by lipoxamycin.The Journal of Antibiotics, 1994
- Sphingolipid breakdown products: anti-proliferative and tumor-suppressor lipidsBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1993
- Inhibition of Sphingolipid Synthesis by Cycloserine In Vitro and In VivoJournal of Neurochemistry, 1984