Effectiveness of Thrombolytic Therapy for Acute Myocardial Infarction in the Elderly

Abstract
LARGE randomized clinical trials1-10 involving about 60 000 patients worldwide have confirmed that thrombolytic therapy can substantially increase survival among patients with acute myocardial infarction (AMI), reducing absolute mortality by 20 to 30 per thousand treated.10 As a result, many national treatment guidelines and quality assurance programs have strongly recommended use of these agents among younger and elderly AMI patients.11-14