Canine Limbic System Substance P Receptors
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Journal of Receptor Research
- Vol. 6 (2) , 141-153
- https://doi.org/10.3109/10799898609073929
Abstract
A canine limbic system preparation is utilized as a source of substance P receptor(s) to screen gradient RP-HPLC fractions for the presence of receptoractive-substance P activity, and to quantify endogenous receptoractive-substance p in biological extracts such as human tooth pulp. The binding characteristics, KD = 1.3 nM and Bmax = 11 fmol mg-1 protein, are similar to values obtained from receptors produced from other biological sources such as whole rat brain, minus cerebellum.This publication has 11 references indexed in Scilit:
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