Anticipating the $1,000 genome
Open Access
- 1 January 2006
- journal article
- opinion
- Published by Springer Nature in Genome Biology
- Vol. 7 (7) , 112
- https://doi.org/10.1186/gb-2006-7-7-112
Abstract
A new generation of DNA-sequencing platforms will become commercially available over the next few years. These instruments will enable re-sequencing of human genomes at a previously unimagined throughput and low cost. Here, I examine why the $1,000 human genome is an important goal for research and clinical diagnostics, and what will be required to achieve it.Keywords
This publication has 15 references indexed in Scilit:
- Spectrum of CHD7 Mutations in 110 Individuals with CHARGE Syndrome and Genotype-Phenotype CorrelationAmerican Journal of Human Genetics, 2006
- Emerging technologies in DNA sequencingGenome Research, 2005
- A haplotype map of the human genomeNature, 2005
- Genome sequencing in microfabricated high-density picolitre reactorsNature, 2005
- Mutations of the SBDS gene are present in most patients with Shwachman-Diamond syndromeBlood, 2004
- Finishing the euchromatic sequence of the human genomeNature, 2004
- Identifying and characterizing a novel activating mutation of the FLT3 tyrosine kinase in AMLBlood, 2004
- EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib TherapyScience, 2004
- A Sequencing Method Based on Real-Time PyrophosphateScience, 1998
- Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic AcidNature, 1953