Heterologous expression, purification, reconstitution and kinetic analysis of an extended type II polyketide synthase
- 1 September 1999
- journal article
- Published by Elsevier in Chemistry & Biology
- Vol. 6 (9) , 607-615
- https://doi.org/10.1016/s1074-5521(99)80112-4
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- Ability of Streptomyces spp. aryl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthaseChemistry & Biology, 1997
- The Streptomyces glaucescens tcmKL polyketide synthase and tcmN polyketide cyclase genes govern the size and shape of aromatic polyketidesJournal of the American Chemical Society, 1995
- Engineered Biosynthesis of Novel Polyketides: Analysis of tcmN Function in Tetracenomycin BiosynthesisJournal of the American Chemical Society, 1995
- Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursorChemistry & Biology, 1994
- Engineered biosynthesis of novel polyketides: Stereochemical course of two reactions catalyzed by a polyketide synthaseBiochemistry, 1994
- Relaxed Specificity of the Oxytetracycline Polyketide Synthase for an Acetate Primer in the Absence of a Malonamyl PrimerJournal of the American Chemical Society, 1994
- Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicinGene, 1994
- Engineered biosynthesis of novel polyketides: manipulation and analysis of an aromatic polyketide synthase with unproven catalytic specificitiesJournal of the American Chemical Society, 1993
- Isolation and Structural Elucidation of Tetracenomycin F2 and Tetracenomycin F1: Early Intermediates in the Biosynthesis of Tetracenomycin C in Streptomyces glaucescensJournal of Natural Products, 1993
- Mutactin, a novel polyketide from Streptomyces coelicolor. Structure and biosynthetic relationship to actinorhodinThe Journal of Organic Chemistry, 1990