Tyrosine hydroxylase and levodopa responsive dystonia.
- 1 January 1989
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 52 (1) , 112-114
- https://doi.org/10.1136/jnnp.52.1.112
Abstract
It has been suggested that a form of inherited dystonia responsive to levodopa might be due to an abnormality of the tyrosine hydroxylase gene. This hypothesis has been tested using a cDNA tyrosine hydroxylase gene probe in three families with this disorder. No evidence for genetic linkage between the disease and tyrosine hydroxylase loci was found; it is possible that the disorder results from a post-transcriptional defect confined to the brain.This publication has 11 references indexed in Scilit:
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