Influence of Cholinergic Receptor Blockade and Stimulation on the Anterior Pituitary Mitotic Activity
- 1 January 1978
- journal article
- research article
- Published by S. Karger AG in Neuroendocrinology
- Vol. 26 (2) , 85-92
- https://doi.org/10.1159/000122772
Abstract
Effects of pilocarpine and atropine on mitotic incidence in the anterior pituitary in male and ovariectomized estradiol-pretreated female rats was investigated. Pilocarpine apparently stimulated, while atropine inhibited, anterior pituitary mitotic activity. Carbachol enhanced the mitotic incidence in the organ-cultured anterior pituitary, and its effect was blocked by scopolamine. The existence of the muscarinic cholinergic receptor within the anterior pituitary, and its involvement in control of the anterior pituitary mitotic activity, is suggested.This publication has 0 references indexed in Scilit: