Ultrasonography of alcoholic liver disease with histological correlation.

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Abstract
In alcoholic liver disease (fatty infiltration, alcoholic hepatitis or cirrhosis), the liver is diffusely abnormal on ultrasound. Changes in size, dilatation of the hepatic veins and ascites may also occur. A histological correlation of these abnormalities in 22 alcoholic patients and 16 controls was conducted and changes on a scale of 0-4+ were made for fat, fibrosis and necrosis and tumor was noted. Ultrasound detected abnormality in 21 cases (sensitivity = 95%) and correctly identified 15 controls (specificity = 94%). Of the 5 tumors seen, 4 hepatomas were detected and biopsied and 1 metastatic squamous-cell carcinoma was missed. Applications of a commercially available A-scan module were considered and its limitations discussed. With the exception of minimal change (1+ fat or fibrosis), ultrasound detected many pathological changes seen in alcoholic liver disease.

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